The Skin Microbiome

The skin is a complex barrier organ made of a symbiotic relationship between microbial communities and host tissue via complex signals provided by the innate and the adaptive immune systems.  It is constantly exposed to various endogenous and exogenous factors which impact this balanced system potentially leading to inflammatory skin conditions comprising infections, allergies or autoimmune diseases. The skin barrier and the microbiota act like a shield that protects the body against external aggressions. There is a balanced interplay between the host and resident and/or transient bacterial populations. This balance is continuously affected by intrinsic (host) and extrinsic (environmental) factors that alter the composition of skin microorganism communities and the host skin barrier function. Altering this equilibrium is called dysbiosis. Therefore, improving the knowledge about the skin microbiome may open new perspectives in the management of the healthy and diseased skin and of its microbiome.

 

  • Cutaneous microbiota
  • Microbiotic diversity
  • Metagenome
  • Dysbiosis of the microbiota
  • Sampling methods

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